House episode analysis

Diseases:

1. Contact Dermatitis: Contact dermatitis is an inflammation of the skin caused by direct contact with an irritating substance.

- House diagnosed this allergy that the nun developed an allergic reaction to the soap for washing dishes.

2. Chug-strauss syndrome: is a disorder marked by blood vessel inflammation. This inflammation can restrict blood flow to vital organs and tissues, sometimes permanently damaging them.

-Causes: The cause of the syndrome is not known, but it involves an abnormal over-activation of the immune system in a person with underlying bronchospastic lung disease (asthma).

3. Thyrotoxicosis: is a condition in which the thyroid gland produces excess thyroid hormone (thyroxine) which results in effects on the whole body.

- Causes: Most often the cause seems to be the body developing an immune reaction against itself, in this case the parts of the thyroid cells which normally act as the receptors for thyroid stimulating hormone (TSH), which is the hormone coming from the gland hanging beneath the brain (the pituitary gland). This hormone normally stimulates the thyroid to produce thyroxine, so antibodies bound on to these receptors cause production of thyroid hormone, and because it attaches to these receptors better than TSH would, more thyroxine than usual is produced.

4. Mixed connective tissue disease: is an uncommon autoimmune disorder that causes overlapping features of primarily three connective tissue diseases — lupus, scleroderma and polymyositis.

-Causes: Doctors don't know what causes mixed connective tissue disease. The disease is part of a larger group of diseases known as autoimmune disorders.

5. Mast cell leukemia: is the aggressive, terminal result of mast cell sarcoma and is a subtype of acute myeloid leukemia.

Treatments:

1. Diphenhydramine: (a pill) is an antihistamine used for treating allergic reactions. Histamine is released by the body during several types of allergic reactions and--to a lesser extent--during some viral infections, such as the common cold . When histamine binds to its receptors on cells, it stimulates changes within the cells that lead to sneezing, itching, and increased mucus production. Antihistamines compete with histamine for cell receptors; however, when they bind to the receptors they do not stimulate the cells. In addition, they prevent histamine from binding and stimulating the cells. Diphenhydramine also blocks the action of acetylcholine (anticholinergic effect) and is used as a sedative because it causes drowsiness. The FDA originally approved diphenhydramine in 1946.

2. Prednisone: is in a class of drugs called corticosteroids. Prednisone prevents the release of substances in the body that cause inflammation.

3. hyperbaric oxygen chamber: is defined as a treatment mode in which the patient is entirely enclosed in a pressure chamber breathing oxygen at a pressure greater than one atmosphere.